Every word is important. You need to open with a bang,too.
You’ve identified a potential employer either throughnetworking- 81% of employers cite that most of their employees were found through networking. Use a name opening when you can. If responding to a blind ad, Dear Prospective Employer: works.
Now, it’s more effective to use numbers and percentages. Sometimes,a quote is used maybe to demonstrate your work ethic or overarching philosophy. The employer wants to know that, not only can you have the qualifications, do you also fit in with the company culture?
Another opening could be a question- the idea being that the employer will be curious or compelled to meet you.
Whatever format you choose, you have to feel comfortable with this decision.
When in doubt, consult a Career Professional.